NEW MED AVAILABLE NOW - Linaclotide (Linzess) for #IBS Constipation - Drug Profile

AVAILABLE NOW -  NEW MED FOR IBS (Type - Constipation) - Linaclotide (Linzess) IBS and Constipation Drug Side Effects, Dosage - MedicineNet:
As of August 2012 it is an option
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Safety Alert!! issued by The FDA - Drug Product for Infectious Diarrhea

FDA ISSUES SAFETY ALERT ON INTESTINOMICINA, DRUG PRODUCT MARKETED AS TREATMENT FOR INFECTIOUS DIARRHEA

WOW This stuff is just death in a bottle. The article doesn't state if the product is an OTC or prescription drug.  I would say that with the chemicals included in this cocktail of toxic shit, that it would be something the doctor must order.  IDK.  For instance, Im allergic to sulfa med and break out into a rash that's so nasty.  pennicillin and all those antibiotics with "cillin" make me rash up too.  I have no clue what Neomycin would do.
I however, have never seen this drug on any drug store shelves.  As they said it is mostly sold in international grocery stores across the US, maybe this is why.  Really, no one knows what stores this stuff may have been sold in.  Just BEWARE of the stuff in the yellow box.

September 22, 2012 (Washington, D.C.) -- The U.S. Food and Drug Administration is warning consumers not to use Intestinomicina, a drug product manufactured in El Salvador and marketed as a treatment for infectious diarrhea and acute gastrointestinal infections. Consumers who have purchased this product should immediately stop taking it and consult with a health care provider.

Intestinominica contains the prescription drug ingredient, chloramphenicol. Oral forms of chloramphenicol were formally withdrawn from the United States market in July 2012 due to the risk of serious and life threatening injuries.

Intestinomicina is labeled primarily in Spanish and lists the ingredient as “chloramfenicol palmitato,” or chloramphenicol in English, on the label. It can be found in tablet and liquid forms and is manufactured by Laboratorios Lopez. The product has been found in international grocery stores in the United States that feature South and Central American specialty foods and products.

The most serious and life-threatening injury associated with oral chloramphenicol treatment is bone marrow toxicity, which occurs when the body does not produce enough red blood cells, white blood cells, and/or platelets. Certain types of bone marrow toxicity are reversible; however, in rare circumstances it can lead to death. Patients with anemia, low white or red blood cell count, or decreased blood platelets may be at a greater risk of death or serious injury.

The product label also lists antibacterial ingredients including neomycin, an antibiotic often found in topical medications, and sulfonamides, sometimes called sulfa drugs. Neomycin and sulfa drugs have the potential to cause a variety of adverse reactions, ranging from rashes and hives, to severe and life-threatening reactions.

Intestinomicina may also interact with other medications consumers may be taking.

Health care professionals and consumers are encouraged to report any adverse events related to Intestinomicina to FDA’s MedWatch Safety Information and Adverse Event Reporting Program:

• online at http://www.fda.gov/Medwatch/report.htm;
• by phone at 800-FDA-1088 (800-332-1088); or,
• by returning FDA form 3500, available on the MedWatch “Download Forms” page by mail to the address on the pre-addressed form or by fax at 800-FDA-0178. 

Link:  FDA ISSUES SAFETY ALERT ON INTESTINOMICINA, DRUG PRODUCT MARKETED AS TREATMENT FOR INFECTIOUS DIARRHEA | East County Magazine:

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A+ Teleseminar - Jini Patel Thompson Talks Abt How She Healed From #Crohns

JPT Wellness Circle - Teleseminar - Jini Patel Thompson talks about how she healed herself from Crohn's Disease.  It's so good.
Just take some time and listen to this... Her protocol makes so much sense. Healing the body as a whole.  Getting to the root problem of your disease.


http://jptwellnesscircle.s3.amazonaws.com/teleseminars/eft-radio-jini-annabel.mp3

Things You Should Never Say To The Chronically Ill Person | Psychology Today *Full Article*

Good article from Psychology Today regarding the stupid things people say to the chronically ill.
Ya know what, there should be a class called - TACT - 101  hahahaa.  No... seriously, people do not know what to say to people that have an invincible illness or one that is a lifetime. They say rude, uncalled for things that are hurtful.  People should not be subjected to this treatment just because they are ignorant about your condition and lack compassion.

What Those with Chronic Pain or Illness DON’T Want to Hear You Say

Even the well-intentioned often don’t know how to talk to the chronically ill.

Published on June 27, 2012 by Toni Bernhard, J.D. in Turning Straw Into Gold

The purpose of this piece is not to make fun of those whose comments are off the mark; most people have good intentions. I've written it partly because I hope it will make those of us with health difficulties feel less alone and partly because I hope it will help others understand how to communicate with us better.Each of the following comments has been made to me at least once since I became ill in 2001.
“Give me a call if there’s anything I can do.”
It’s highly improbable that this well-intentioned comment will result in my picking up the phone. You’ve put the ball in my court and I’m unlikely to hit it back, either because I’m too shy, too embarrassed, too proud, too sick—or a combination of the four. I’m not going to call and say, “Can you come over and do my laundry?” But if you call and offer to come over and do it, I’ll gratefully say, “yes”!

“I wish I could lie in bed and watch TV all day long.”

It may sound like this couldn’t possibly have been a well-intentioned comment, but given the tone of voice in which it was said to me over the phone, I’m certain it was. I believe that the hard-working friend who said it was genuinely thinking, “Lucky you to have so much leisure time.” When she said it, I was still so sensitive about being sick—including being worried that people might think I was a malingerer—that tears came to my eyes. Then I wanted to scream, “You have no idea how it feels to be sick and stuck in bed with no choice but to watch TV!” Instead of screaming, I mumbled something and got off the phone as soon as I could because I could feel the sobs coming—as they did as soon as I hung up.

 “Disease is a message from your soul, telling you that something is wrong with your True Self.”

This is an excerpt from one of dozens of emails I’ve received from people trying to diagnose and/or cure me. I must admit that I have no idea what that sentence means. Are the soul and the True Self different entities, and the one that is okay is sending a message to the other one saying that something’s wrong with it? Bottom line: This is not helpful! Oh, and another person said she’d assist me to get my health back—free of charge—by showing me how to do soul retrieval. Sigh.

“The third cousin of my brother-in-law’s sister’s best friend had what you have and said she got better by drinking bottled water.”

Another sigh.

“Have you tried sleeping pills?”

Sleeping pills? Who hasn’t tried sleeping pills? Even healthy people do! Sleeping pills may be helpful for some people, but they are not a cure for chronic pain or illness. And while we’re on the subject of “Have you tried…” If it’s available by prescription, I’ve tried it. If it’s available as a supplement, I’ve tried it. If it’s available as a Chinese herb, I’ve tried it. If it’s available at all, the odds are very high: I’ve tried it. 

“Just don’t think about it.”

This comment left me speechless…but still thinking about “it.”

“Aren’t you worried that you’re getting out of shape from living such a sedentary lifestyle?”

Uh...yes. Thanks for reminding me.

“Have you Googled your symptoms?”

Let me count the ways.

“At least you still have your sense of humor.”

Thanks, but I’d rather be known as humorless but healthy.

© 2012 Toni Bernhard

In my article, “What Those with Chronic Pain or Illness DON’T Want to Hear You Say,” I shared some of the comments that have been made to me since I became chronically ill in 2001. Many people shared that they’d been subjected to the very same comments…and more. And so, I’ve put together a small sampling of comments that readers have had to listen to. As I said in the first article, I’m not trying to make fun of others. My intent is to educate people about what we face and also to help us feel less alone.

Bottom line: Fielding these comments with grace and skill is yet another challenge faced by those of us with health problems. I’ve divided the comments into five categories:Change Your Lifestyle; Such an Easy Life…; Chronic Means Chronic; It’s Your Fault; and Religion and other SpiritualMatters.

Change Your Lifestyle
1. “Do you take vitamins?” This comment reminds me of the people who’ve asked me if I’ve tried sleeping pills. Who hasn’t taken vitamins?!

2. “Are you eating enough fruits and vegetables?” Lots of people report getting asked this.

3. “Just eat more.”

4. “Just eat less.” (This one forms a nice symmetry with #3.)

5. “Are you drinking water?”

6. “You just need some fresh air and exercise, that’s all.”

7. “Why don’t you go to bed earlier?”

8. “Why don’t you take a shower? You’ll feel better.” This one hit home with me because I have days when taking a shower has the opposite effect: this simple task uses up all my energy stores for the day.

Such an Easy Life…

1. One woman wrote: “I mentioned to a friend when I got to his kid’s birthday party that I almost didn’t make it because I’d been in bed most of the weekend and it was hard getting out of the house. He said, ‘You have such an easy life!’”

2. Wrote another woman: “It’s frustrating when someone thinks you are ‘lucky’ to have so much leisure time available. Yeah, it’s great to have so much time, but I’m unable to work and thus am so far below the poverty line that homeless people begging for change probably have more money at their disposal than I do.”

This raises what I think is a hidden epidemic for those with chronic health problems. Many are living below the poverty line, due to a combination of not being able to work and of having to spend any money they do have on medications and other treatments that health insurance doesn’t cover—if they’re lucky enough to even have health insurance. Tragically, poverty, chronic pain, and chronic illness too often go hand in hand.

3. Finally, this woman sums up “Such an Easy Life…” as well as I could:“My favorite is when people say I’m lucky that I don’t have to work. It’s like telling someone without legs they’re lucky they don’t have to take the stairs.”

Chronic Means Chronic

1. Several people wrote that they’ve been asked, “You’re STILL in pain?”Many people have said to me: “You’re STILL sick?” Yes, we’re still sick and we’re still in pain because…chronic means chronic!

2. Said to a person with chronic pain: “Don’t worry, you’ll be able to go hiking again soon.” I’ve had people say this to me about many activities—from traveling to resuming my teaching career. I think that if you’re not sure what a friend might or might not be able to do in the future, it’s better not to raise it.

3. “Call me when you feel better and we'll go to lunch or do something fun." Again, chronic means chronic.
4. “My mother-in-law had that and all she did was take a little Tylenol.”Sigh.

5. “At least it’s not cancer.” This comment doesn’t fit neatly under any of the categories I’ve used, but I wanted to include it because several people reported having had this said to them. It’s not helpful. In fact, one woman wrote that at least if she had cancer, her family would get more support both from the medical community and from their church congregation.

It’s Your Fault

I recognize that this category is subjective. Comments that I interpret as implying, “It’s your fault,” may not seem that way to others. That said, here’s a sampling of comments that, to me, are suggesting to a person who is sick or in pain: it’s your fault.

1. “You’re too young to be sick,” several people reported being told. One of them added: “Oh, how wish this were true. Maybe by the time I’m in my 80s, people will stop saying it.”

2. One woman reported that her friend, after listening with “a seemingly caring ear,” said: “Attitude is everything, you know.”

3. A young woman wrote that she’s been told to distract herself from chronic pain by “getting a job, mingling with people, and engaging mybrain.” About these comments, she said: “I’m sensitive about being perceived as lazy. I’m hurt whenever this comment is made to me. I’d love to be able to will myself to do whatever I’d like.” This resonated strongly with me because I spent years trying to will my body into good health. All I got for my effort was a lot of mental suffering added to the suffering of the illness.

4. “You must be out of alignment with your life and looking for an excuse to make some changes.” The recipient of this comment said, “But some of us really loved our life before we got ill.” To that, I say, “Yes. Yes”! I was never happier—personally and professionally—than when I got sick in 2001.

5. “Maybe if you quit talking about it, you’ll get better.”

6. “Look what happens when you don’t look after yourself.”

7. “Just snap out of it.” The woman who reported this comment went on to say: “Like it’s really that simple and I’m so totally dumb and stupid that can’t figure it out. How silly of me after so many years.”

8. Saving the worse for last, a person reported that his or her doctor said:“If you think of yourself as a cripple, you will become a cripple.” This comment is hurtful and inappropriate in so many ways.

Religion and other Spiritual Matters

This is a sensitive topic. We all have our particular religious and spiritual beliefs and they may understandably feel essential to our well-being. But in my opinion, religious and spiritual beliefs are so personal that unless you know that the person you’re talking to shares your beliefs, it's better not to raise the subject. As one person commented: “The assumption that all of us have or even should have identical spiritual beliefs is unrealistic in our pluralistic society. If you're not sure you're on the same track, it might best be avoided.”

Keeping in mind that this is a sensitive topic, I offer some comments that have been directed at those struggling with their health.

1. Two people wrote that they’ve repeatedly been told, “God never gives us more than we can handle,” and that it’s not at all consoling to them. In fact, they said it makes them feel like failures—as if they’re not handling well what they should be handling well.

2. “God has a plan for your life.”

3. “All things work for the Good for those who love God.” The woman who reported this comment wrote about it: “There’s nothing more annoying than some random bible quote thrown into your face as a ‘reason’ for chronic pain.”

4. “If you pray to God harder and longer, He will cure you.”

5. “The universe is trying to teach you something.”

6. One woman wrote that her brother repeatedly says to her, “Obviously you don’t pray to God enough because if you did, he would heal you. So you must be doing something wrong.” She said that every time he says this, she bursts into tears because she feels blamed for not doing enough to get better.

I’ve found that many comments about religion, regardless of the speaker’s intent, leave people that they’re spoken to feeling as if it’s their fault that they’re sick or in such pain. And so, these comments could have gone under the previous heading: It’s Your Fault.

Toni Bernhard, J.D.

Until forced to retire due to illness, I was a law professor for 22 years at the University of California — Davis, serving six years as the law school’s dean of students. Author of How to Be Sick has won two 2011 Nautilus Book Awards: A Gold Medal in Self-Help/Psychology and a Silver Medal in Memoir. It was also named one of the best books of 2010 by Spirituality and Practice.  My new book, World of Joys, World of Sorrows, will be published in the Fall of 2013. 
Direct Links:
What Those with Chronic Pain or Illness DON’T Want to Hear You Say | Psychology Today:
More On: What Those with Chronic Pain or Illness DON’T Want to Hear You Say | Psychology Today:
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Morinaga BB536® - A Top Selling Probiotic with 40 Clinical Trials to Support the Benefits - PDF file DL

Morinaga Maypro has put together a file of 40 clinical trials over the span of  30 years ,that looks at different issues in the body from digestive support to immunity to infant health and more, all of the studies used the BB536 probiotic.  Interesting to read the various issues and how this probiotic worked for each .  You can click the link at the bottom of the page to download the 32 page PDF file with all the 40 clinical trials.  All you have to do is fill out the form.  OR if you send me an email or private message with an e-mail address, I can e-mail the pdf file right to you.

Published: 07-Sep-2012 Format: PDF file Length: 32 Page(s) Type: Clinical Study

Morinaga BB536® - Japan’s Top-Selling Clinically Proven Probiotic

In breastfed infants, an astonishing 90% of the bacterial colonies in the GI tract are made up of bifidobacteria.  As we age, the presence of Bifidobacterium longum in particular drops precipitously leaving only an average of 5% of the original colonies in an adult intestinal tract.  Since it is often replaced with harmful bacteria such as E.coli, the case for nutritional supplementation with bifidobacterium longum is strong.

But not all strains within this species are created equal.  Morinaga BB536 is supported by40 human clinical studies showing a range of benefits for digestive support, immunity, healthy response to seasonal challenges and infant health.  BB536 also offers unparalleled stability, showing 80% active cell counts after 48 months at room temperature.

Clinical study

Morinaga BB536® - Japan’s Top-Selling Clinically Proven Probiotic:

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Mayo Clinic MD Discusses A Good Option For Severe Cases of Ulcerative Colitis

The doctor explains the surgery for an ileoanal anastomosis and discusses the benefits of this surgery for hard to treat UC (ulcerative colitis).

"...ileoanal anastomosis eliminates ulcerative colitis. Bowel movements after surgery can be more frequent, and they may be watery or soft because the colon is not present to absorb water. But, for most people, symptoms such as pain, cramps, diarrhea and urgent bowel movements disappear after ileoanal anastomosis and, as a result, their overall quality of life is much better than it was before surgery."

— John Pemberton, M.D., Colon and Rectal Surgery, Mayo Clinic, Rochester, Minn. 

CLICK LINK TO READ MORE.......

Procedure Can Significantly Improve Quality of Life for Those with Severe Ulcerative Colitis:

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WHat's for Lunch? Some Genetically Engineered Meatloaf - Read About This Totally Unnatural Process!

Mmmmm Yummy Genetically modified/engineered food!!  Soundsl like it is.... Straight up UNHEALTHY!  Then  people wonder why they have auto-immune diseases.  Reading this "These new life forms have unpredictable behavior and replicate themselves out of control in the wild. They take shape as super weeds, super bugs and as super viruses inside our bodies. - VILE!  I can almost feel the "super bugs" searching for the super weeds inside my body!!  

It's horrible that this type of shit garbage is even allowed inside a grocery store.  Lowered standards man.  

Vote 'yes' on 37

http://www.timesheraldonline.com/letters/ci_21532581/vote-yes-37

Published By Times Herald

Posted:   09/13/2012 01:04:19 AM PDT

Got food allergies, cancer, Parkinson's disease, Crohn's, faulty insulin regulation (diabetes), irritable bowel syndrome, leaky gut, autism, infertility problems, auto-immune deficiencies? All these illnesses and conditions could be the result of genetically engineered food, says the Union of Concerned Scientists (a 400,000-plus member, science-based nonprofit organization) and the Institute of Responsible Technology (educator for policy makers and the public).
Genetic engineering (GE) or genetic modification (GM) is done in a lab with a gene gun, or using bacteria or viruses to infect cells and alter their DNA structure. The cells are then cloned into plants. The genetic consequences are unpredictable and bear no relation to the natural plant breeding that farmers have been doing for hundreds of years. The National Research Council says that unintended changes arise with ALL forms of genetic modification. According to the National Research Council: "All evidence evaluated to date indicates that unexpected and unintended compositional changes arise with all forms of genetic modification, including genetic engineering."

Since 1996, our food supply has been genetically engineered to the point that an estimated 70 percent of the foods on grocery store shelves now contain genetically modified ingredients. There have been no long-term health studies nor has the Food and Drug Administration been vigilant in protecting consumers from the perils of genetically modified foods

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despite warnings from their own scientists.
The risks of genetically modified foods and organisms are multi-dimensional. They include the creation of new "transgenic" life forms (organisms whose genome has been altered by messing with its DNA). These new life forms have unpredictable behavior and replicate themselves out of control in the wild. They take shape as super weeds, super bugs and as super viruses inside our bodies. With all this genetic pollution going on, it should not be surprising that the health of our families is on the demise.

Please vote "yes" on Proposition 37 -- the "right-to-know" initiative to label GE foods. The giant agriculture and food manufacturing companies will try to fool us into believing that GE foods are safe and that it will cost the consumer more to label these foods. Companies change their labels all the time to take advantage of latest marketing trends. Let's vote "yes" on 37 and make labeling genetically modified foods the next new marketing trend and put to rest this death-delivering technology by giving consumers the right to know and the right to choose.



Christine Long

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People With IBD Have A Higher Chance For Ischemic Heart Disease | Study Published in GUT

What else are we at risk of?? My God!  It gets so annoying reading negative all the time.  I will find a few good positive reports today..  I have to.

Anyway.. this is a great study because it's large.  The more people they have, the better. I'd say that based on that alone, the results of the study are pretty accurate and right on.

"Risk for ischemic heart disease was higher among patients with IBD than those without, particularly within 1 year of IBD diagnosis in a recent study."

Patients with IBD at increased risk for ischemic heart disease | Gastroenterology:

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Glenmark Pharmaceutical Enters Phase II Trial- A New Drug That Seeking Safer and More Effective Treatments for IBD

NEW DELHI, SEPT 13: 

Glenmark enters phase II trial for new drug molecule aimed to treat Ulcerative colitis.

But 1st what exactly does this drug do.  How does it work?  I wanted to find out  - Here's some info - GBR 500, a novel monoclonal antibody for the treatment of Crohn's Disease and other inflammatory conditions.

GBR 500 is an antagonist of the VLA-2 (alpha2-beta1) integrin. It is a first-in-class therapeutic monoclonal antibody and has established proof of concept in animal models across a range of anti-inflammatory conditions. Glenmark has completed Phase I dosing of GBR 500 in the US and the drug has been well tolerated with a good pharmacokinetic profile. Plans are in place to initiate clinical proof of concept studies in Crohn's Disease. Sanofi has licensed the rights to all therapeutic indications.

"There continues to be a strong medical need for safer and more efficacious products for the treatment of Inflammatory Diseases," said Elias Zerhouni, M.D., President, Global Research & Development, Sanofi. "GBR500 brings an innovative approach to Sanofi's Immuno-Inflammation portfolio, which we believe may address a significant gap in treating Inflammatory Diseases which would be of huge benefit to patients".

Reference:  Glenmark Pharmaceuticals Out-Licenses Novel Monoclonal Antibody, GBR 500, to Sanofi -- MUMBAI, India, May 16, 2011 /PRNewswire-FirstCall/ --

Now on with the article about Glenmark Pharm entering into phase II .......

Glenmark Pharmaceuticals today said that it has entered the phase II clinical trials for its new drug molecule aimed at treating ulcerative colitis.

The company’s subsidiary Glenmark Pharmaceuticals SA will conduct trials at multiple clinical sites in North America and Europe to investigate the efficacy and safety of the new molecule GBR 500, Glenmark Pharmaceuticals said in a statement.

It is expected that the trial will include nearly eighty four patients with moderate to severe ulcerative colitis, it added.

Commenting on the development, Glenmark Pharmaceuticals Chief Scientific Officer Michael Buschle said: “Despite treatment advances in recent years, ulcerative colitis remains a debilitating condition for many individuals, and represents an area of substantial unmet medical need.”

    This phase II clinical trial is part of a global collaboration between Glenmark and Sanofi to investigate GBR 500 for the treatment of chronic inflammatory disorders, the company said.

Sanofi has been licensed the rights to all therapeutic indications and is conducting the clinical development programme including this trial, it added.

Individuals participating in the study will receive multiple doses of either GBR 500 or placebo, administered over a period of several weeks, it added.

In the Phase II clinical trials of drug development, a larger group of people (100-300) is given experimental treatment to check the efficacy and safety of the molecule.

The company has completed Phase I trials (done on a smaller set of human subjects) of GBR 500, a monoclonal antibody in the US, Glenmark said.

Shares of Glenmark Pharmaceuticals were today trading at Rs 435 per scrip on BSE, up 0.88 per cent from their previous close.

LINK  ->
Business Line : Companies News : Glenmark enters phase II trial for new drug molecule:

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