Crohn's can be associated with so many factors, but the progression to determine more components about that factor "A", may lead to other discoveries that bring understanding about how "A" and "B", but not enough to progress with more research studies.
Then ... That's it! Scientists reach dead ends. It seems as if the findings discovered do not provide enough concrete information to bring more understanding about the disease which halts additional research You never hear much more about the relationship between A & B again. This happens so much with so many of the studies that seek to understand the disease and they all seem to reach a dead end at some point during the research. There's a few factors that have a pretty good progression that continue to lead to more connections; & its MAP. It is the only information that I have read and continue to read that discover new findings and links to Crohn's. Scientists are able to get somewhere with their findings that allow them to be able to do more studies and they gain more understanding about the disease.
The other factor that stands out is the Hygiene Hypothesis. Read about it, it makes sense.
Of all the conditions we would have to have is one as complicated as the Crohn. I associate the Crohn's with a nightmare person that is sorta like a stalker/rude/unpredictable/enjoys messing up my day(s) and overstays their welcome ... but they were never welocome to begin with ... The nightmare just comes right in and makes itself at home.
Anyway... enough of my babble. Feel free to comment on your thoughts on what research seems to stand and make progress toward an effective treatment and maybe even a cure. I'd love to hear what you've found .