Dificid Approved to Treat iC. diff/i Diarrhea --Doctors Lounge
I'm posting this article because C. diff., a bacteria infection that is usually contracted in hospitals that causes severe diarrhea and in some cases can cause colitis or even death, can be treated by a new drug that was just FDA approved. The drug Dificid is said to be effective with treating the continual diarrhea that C. diff. infected sufferers experience.
I do not know anyone that has been prescribed this medication yet, but I like to know that there are other options for treatment that are available for people with this infection. Hospitals are the most common place where people become infected with C. diff. I have two family members that became ill with this infection during their stay in the hospital. Both my Aunt and Grandmother were plagued with the persistent and temporary debilitating C. diff. Some people cannot leave the house due to symptoms and sometimes the infection lasts for months and if you're an unfortunate one, the bacteria infection can recur at some point in the future.
What I know for a fact that works for helping eliminate and calm symptoms is taking a good probiotic. This was the ONLY helpful thing my Aunt took that helped her get better & back to normal. You must replenish your gut flora that is killed by the bacteria & also killed by the prescribed antibiotic, leaving you with no good bacteria in your gut = not good.
Monday, August 15, 2011
Sunday, August 14, 2011
Nanoparticle Iron & Minerals - A Good Option for IBS & IBD Sufferers That Require Supplemental Nutrients
I'm really interested in learning more about Nanoparticle Medicine/Nanoparticle Technology for drug and mineral delivery. What I've read about the stuff is that Nanoparticles & products of nanotechnology are of increasing interest to the pharmaceutical community. They can increase drug solubility, enhance bioavailability, allow tissue targeting, offer decreased side-effects, and improve therapeutic efficacy.
Drug delivery technologies are patent protected formulation technologies that modify drug release profile, absorption, distribution and elimination for the benefit of improving product efficacy and safety, as well as patient convenience and compliance.[3] Most common routes of administration include the preferred non-invasive peroral (through the mouth), topical (skin), transmucosal (nasal, buccal/sublingual, vaginal, ocular and rectal) and inhalation routes.[4][5] Many medications such as peptide and protein, antibody, vaccine and gene based drugs, in general may not be delivered using these routes because they might be susceptible to enzymatic degradation or can not be absorbed into the systemic circulation efficiently due to molecular size and charge issues to be therapeutically effective. For this reason many protein and peptide drugs have to be delivered by injection or a nanoneedle array.
Because I have to always get iron infusions; about every 3 months or so, it would be so wonderful to be able to orally take the iron without experiencing stomach and intestinal bleeding/upset. I absolutely cannot tolerate regular oral iron capsules or tablets whatsoever. Due to the ongoing intestinal bleeding, I lose a significant amount of blood; enough to lower my red blood cell count causing me to become anemic. The only safe and tolerable solution to raise my level of iron is through a 5-7 session round of 30-45 min. Iron Sucrose infusions every few months. I tried the 2 session Iron infusion ( kind of like one big dose of iron injected within 20 seconds rather than 20 min, requiring only 2 injections) and had a reaction. My body is a fragile, sensitive thing and reacts to so many chemicals, foods, plants, people... yes humans lol... just kidding about the people and plants, unless they're pollenated and say stupid things.
Discovering the Nanoparticle form of iron seems like something that I may be able to handle because the iron is instantly absorbed into the bloodstream and does not require digestion. This Means that in this form, it will not irritate the GI tract and this is AWESOME news because Iron infusions are $CoStLY$ (Approximate cost for just 1 - 30 min infusion amounts to say $580. $600.- or close to that amount PER infusion. $400 for just the iron alone is just wrong, so if I can find an effective and reasonable priced way of addressing this bitch called anemia, I will jump on the chance to try it out.
Has anyone ever tried something like this in any mineral form? If so, I'd like to get your input.
Once I located a reputable source of Nanoparticle Iron, I will post the manufacturer and the effects of taking this type of iron.
LINK WITH MORE INFO & A SOURCE WHERE YOU CAN PURCHASE NANOPARTICLE IRON + VITAMIN C http://www.holistichealthshoppe.com/astragalus.php?id=24#262
Drug delivery technologies are patent protected formulation technologies that modify drug release profile, absorption, distribution and elimination for the benefit of improving product efficacy and safety, as well as patient convenience and compliance.[3] Most common routes of administration include the preferred non-invasive peroral (through the mouth), topical (skin), transmucosal (nasal, buccal/sublingual, vaginal, ocular and rectal) and inhalation routes.[4][5] Many medications such as peptide and protein, antibody, vaccine and gene based drugs, in general may not be delivered using these routes because they might be susceptible to enzymatic degradation or can not be absorbed into the systemic circulation efficiently due to molecular size and charge issues to be therapeutically effective. For this reason many protein and peptide drugs have to be delivered by injection or a nanoneedle array.
Because I have to always get iron infusions; about every 3 months or so, it would be so wonderful to be able to orally take the iron without experiencing stomach and intestinal bleeding/upset. I absolutely cannot tolerate regular oral iron capsules or tablets whatsoever. Due to the ongoing intestinal bleeding, I lose a significant amount of blood; enough to lower my red blood cell count causing me to become anemic. The only safe and tolerable solution to raise my level of iron is through a 5-7 session round of 30-45 min. Iron Sucrose infusions every few months. I tried the 2 session Iron infusion ( kind of like one big dose of iron injected within 20 seconds rather than 20 min, requiring only 2 injections) and had a reaction. My body is a fragile, sensitive thing and reacts to so many chemicals, foods, plants, people... yes humans lol... just kidding about the people and plants, unless they're pollenated and say stupid things.
Discovering the Nanoparticle form of iron seems like something that I may be able to handle because the iron is instantly absorbed into the bloodstream and does not require digestion. This Means that in this form, it will not irritate the GI tract and this is AWESOME news because Iron infusions are $CoStLY$ (Approximate cost for just 1 - 30 min infusion amounts to say $580. $600.- or close to that amount PER infusion. $400 for just the iron alone is just wrong, so if I can find an effective and reasonable priced way of addressing this bitch called anemia, I will jump on the chance to try it out.
Has anyone ever tried something like this in any mineral form? If so, I'd like to get your input.
Once I located a reputable source of Nanoparticle Iron, I will post the manufacturer and the effects of taking this type of iron.
LINK WITH MORE INFO & A SOURCE WHERE YOU CAN PURCHASE NANOPARTICLE IRON + VITAMIN C http://www.holistichealthshoppe.com/astragalus.php?id=24#262
Friday, August 05, 2011
Texas Lawsuit Against Abbott - Claiming Humira-Induced Leukemia In Young Patient. Do The Benefits Outweigh The Side Effects With This Med?
Article about 11 year old boy who was diagnosed with T cell acute lymphoblastic leukemia after taking the drug Humira for psoriasis, a skin condition. Lawsuit filed in Texas against Abbott Labs.
What do people think about in regards to the conditions that the drug Humira treats vs the possible life-threatening side-effects Humira causes? What's worse: (disease being treated, such as) arthritis, ankylosing spondylitis, crohn's disease, plaque psoriasis OR (Humira side-effects like...) cancer, possible serious allergic reactions, Hepatitis B virus reactivation, nervous system problems, serious infections, heart failure, blood issues and certain immune reactions? Just wondering what other people's take is on this. For me, I'd rather have Crohn's than Cancer. Even although Crohn's Disease is extremely painful and debilitating, so is cancer. When people choose to say "Yes" to a treatment like Humira or Remicade, do the people have all the knowledge (good & bad) about the medication to make the right decision on which treatment option is the best and healthiest for them?
I feel like most patient's leave it up to their doctor's to make that decision and put too much trust in them. People hear "this medication works and will get rid of your symptoms" from their doctors and automatically jump on the Humira Train/Remicade Bus ect.
Despite what our doctor says, we need to do adequate research so we can know what's necessary about the treatment we agree to. Just my personal opinion.
Perdue Kidd & Vickery Files Lawsuit Against Abbott Laboratories for Inadequate Leukemia and Cancer Warning
Drug Humira Blamed for Boy's Leukemia Diagnosis
DALLAS, July 29, 2011 /PRNewswire/ -- Humira defect lawyers filed a lawsuit against Abbott Laboratories in Texas state court claiming Abbott's blockbuster drug, Humira, caused a life-threatening disease, leukemia.
"Eleven year-old Bo Anderson was prescribed Humira for a skin condition, psoriasis. After taking the drug for approximately ten months, Bo's parents noticed unusual bruising covering his body while on a family vacation," says drug defect attorney Andy Vickery.
"Bo immediately underwent various tests and was diagnosed with T cell acute lymphoblastic leukemia; a dangerous side effect Abbott Laboratories knew could affect Humira users but failed to warn them about."
Vickery says because of the Humira-induced leukemia, Bo now must continue to undergo intense treatment that could potentially cause long-term and serious side effects, and could possibly develop secondary cancers as he matures.
Prior to the launch of Humira in 2003, other similar drugs had been linked to lymphoma and other forms of cancer, and clinical trial data suggested that there was a very significant epidemiological "signal" about the risk. Once Humira was launched, many adverse event reports were submitted regarding cancers, however Abbott did nothing to warn about this. Bo was diagnosed with Leukemia on January 8, 2009, over seven months after the FDA said that physicians and patients should be warned about this side effect, and nearly ten months before a Black Box warning was finally issued regarding Humira-induced leukemia in pediatric and adolescent patients.
Humira (Adalimumab) is a class of biologic drugs known as TNF (Tumor Necrosis Factor) blockers. It works by blocking naturally occurring proteins that cause inflammation. However, research has shown that taking drugs like Humira can compromise the immune system and can have a devastating and even deadly effect resulting in serious infections, cancer, allergic reactions, Hepatitis B virus reactivation, nervous system problems, heart failure, blood issues and certain immune reactions. Humira is used for the treatment of rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, crohn's disease, and plaque psoriasis. With 2010 sales of $6.5 billion, Humira is Abbott's flagship drug.
Perdue Kidd & Vickery is a national law firm of Board Certified Personal Injury Trial Lawyers. The law practice is based in Houston, TX. Further information is available at http://www.HumiraJustice.com. View an educational video about Humira fungal infections.
SOURCE Perdue Kidd & Vickery
What do people think about in regards to the conditions that the drug Humira treats vs the possible life-threatening side-effects Humira causes? What's worse: (disease being treated, such as) arthritis, ankylosing spondylitis, crohn's disease, plaque psoriasis OR (Humira side-effects like...) cancer, possible serious allergic reactions, Hepatitis B virus reactivation, nervous system problems, serious infections, heart failure, blood issues and certain immune reactions? Just wondering what other people's take is on this. For me, I'd rather have Crohn's than Cancer. Even although Crohn's Disease is extremely painful and debilitating, so is cancer. When people choose to say "Yes" to a treatment like Humira or Remicade, do the people have all the knowledge (good & bad) about the medication to make the right decision on which treatment option is the best and healthiest for them?
I feel like most patient's leave it up to their doctor's to make that decision and put too much trust in them. People hear "this medication works and will get rid of your symptoms" from their doctors and automatically jump on the Humira Train/Remicade Bus ect.
Despite what our doctor says, we need to do adequate research so we can know what's necessary about the treatment we agree to. Just my personal opinion.
Perdue Kidd & Vickery Files Lawsuit Against Abbott Laboratories for Inadequate Leukemia and Cancer Warning
Drug Humira Blamed for Boy's Leukemia Diagnosis
DALLAS, July 29, 2011 /PRNewswire/ -- Humira defect lawyers filed a lawsuit against Abbott Laboratories in Texas state court claiming Abbott's blockbuster drug, Humira, caused a life-threatening disease, leukemia.
"Eleven year-old Bo Anderson was prescribed Humira for a skin condition, psoriasis. After taking the drug for approximately ten months, Bo's parents noticed unusual bruising covering his body while on a family vacation," says drug defect attorney Andy Vickery.
"Bo immediately underwent various tests and was diagnosed with T cell acute lymphoblastic leukemia; a dangerous side effect Abbott Laboratories knew could affect Humira users but failed to warn them about."
Vickery says because of the Humira-induced leukemia, Bo now must continue to undergo intense treatment that could potentially cause long-term and serious side effects, and could possibly develop secondary cancers as he matures.
Prior to the launch of Humira in 2003, other similar drugs had been linked to lymphoma and other forms of cancer, and clinical trial data suggested that there was a very significant epidemiological "signal" about the risk. Once Humira was launched, many adverse event reports were submitted regarding cancers, however Abbott did nothing to warn about this. Bo was diagnosed with Leukemia on January 8, 2009, over seven months after the FDA said that physicians and patients should be warned about this side effect, and nearly ten months before a Black Box warning was finally issued regarding Humira-induced leukemia in pediatric and adolescent patients.
Humira (Adalimumab) is a class of biologic drugs known as TNF (Tumor Necrosis Factor) blockers. It works by blocking naturally occurring proteins that cause inflammation. However, research has shown that taking drugs like Humira can compromise the immune system and can have a devastating and even deadly effect resulting in serious infections, cancer, allergic reactions, Hepatitis B virus reactivation, nervous system problems, heart failure, blood issues and certain immune reactions. Humira is used for the treatment of rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, crohn's disease, and plaque psoriasis. With 2010 sales of $6.5 billion, Humira is Abbott's flagship drug.
Perdue Kidd & Vickery is a national law firm of Board Certified Personal Injury Trial Lawyers. The law practice is based in Houston, TX. Further information is available at http://www.HumiraJustice.com. View an educational video about Humira fungal infections.
SOURCE Perdue Kidd & Vickery
Monday, July 25, 2011
FDA Does Something Right For A Change - Article still pisses me off though.... of course!
LOL
LOL OMG. If anyone knows me well, they know my blood is boiling right now. I know I bitch a lot about FDA and drug company bullshit all the time, but I read more and more damn nonsense that I can't contain the frustration. Anyone feel me on this Oh.... & I also bitch because I can... It's my freaking blog and i'll say what i want..... DAMN IT!!
i like the numbers.. the beautiful sight of the billion.
"J&J reported Simponi revenue of $67 million in the second quarter and $162 million in the first half of the year. Remicade, which is approved for about a dozen uses in treating various immune disorders, brought J&J about $1.4 billion in the second quarter and $2.7 billion in the first six months of 2011."
the 2nd paragraph to the last should just be deleted from this article. Remicade, Humira, ect., cause the same dangerous side-effect.
FDA rejects new use for J&J immune disorder drug
By LINDA A. JOHNSON
Healthcare giant Johnson & Johnson plans to meet with U.S. regulators after they refused to approve a new use for the company's immune disorder drug, Simponi.
The company, based in New Brunswick, N.J., said Friday night that the Food and Drug Administration notified its Janssen Biotech Inc. subsidiary that it would not approve marketing of Simponi for limiting progression of structural damage in patients with moderate to severe rheumatoid arthritis.
In a statement, Janssen said it will request a meeting with the FDA to discuss the details of the decision and "future steps to achieve the intended approval."
Janssen applied for the approval in September 2010.
Simponi is a genetically engineered antibody drug that tracks down and binds up the protein TNF-alpha in the blood. In some people, the body produces excess levels of this protein, causing inflammation and damage to bones, cartilage and tissue.
Simponi was first approved in 2009 for sale in the U.S., Europe and Canada as a monthly injection for treating psoriatic arthritis, ankylosing spondylitis and, in combination with the drug methotrexate, for moderate to severe rheumatoid arthritis.
This year, the drug was approved in Europe and then Japan for slowing or preventing structural damage from rheumatoid arthritis in certain patients, uses similar to what the company is seeking in the U.S.
"We look forward to collaborating with the FDA to fully understand requirements needed to support" approval of the new use, Dr. Jerome A. Boscia of Johnson & Johnson Pharmaceutical Research & Development, said in a statement.
Johnson & Johnson shares revenue with Merck & Co. from Simponi and its predecessor drug, Remicade, which was approved in November 1999. Merck sells them in Europe, Russia and Turkey. J&J markets them in North, Central and South America, the Middle East, Africa and most of the Asia-Pacific region.
J&J reported Simponi revenue of $67 million in the second quarter and $162 million in the first half of the year. Remicade, which is approved for about a dozen uses in treating various immune disorders, brought J&J about $1.4 billion in the second quarter and $2.7 billion in the first six months of 2011.
Because Simponi suppresses part of the immune system, use can result in serious infections, including tuberculosis.
Other possible side effects, some of them rare, include: unusual cancers in children and teenagers, reactivation of the hepatitis B virus, heart failure, liver problems, bruising and bleeding easily, lupus-like symptoms such as shortness of breath and joint, muscle or chest pain, and nervous system problems such as multiple sclerosis.
LOL OMG. If anyone knows me well, they know my blood is boiling right now. I know I bitch a lot about FDA and drug company bullshit all the time, but I read more and more damn nonsense that I can't contain the frustration. Anyone feel me on this Oh.... & I also bitch because I can... It's my freaking blog and i'll say what i want..... DAMN IT!!
i like the numbers.. the beautiful sight of the billion.
"J&J reported Simponi revenue of $67 million in the second quarter and $162 million in the first half of the year. Remicade, which is approved for about a dozen uses in treating various immune disorders, brought J&J about $1.4 billion in the second quarter and $2.7 billion in the first six months of 2011."
the 2nd paragraph to the last should just be deleted from this article. Remicade, Humira, ect., cause the same dangerous side-effect.
FDA rejects new use for J&J immune disorder drug
By LINDA A. JOHNSON
Healthcare giant Johnson & Johnson plans to meet with U.S. regulators after they refused to approve a new use for the company's immune disorder drug, Simponi.
The company, based in New Brunswick, N.J., said Friday night that the Food and Drug Administration notified its Janssen Biotech Inc. subsidiary that it would not approve marketing of Simponi for limiting progression of structural damage in patients with moderate to severe rheumatoid arthritis.
In a statement, Janssen said it will request a meeting with the FDA to discuss the details of the decision and "future steps to achieve the intended approval."
Janssen applied for the approval in September 2010.
Simponi is a genetically engineered antibody drug that tracks down and binds up the protein TNF-alpha in the blood. In some people, the body produces excess levels of this protein, causing inflammation and damage to bones, cartilage and tissue.
Simponi was first approved in 2009 for sale in the U.S., Europe and Canada as a monthly injection for treating psoriatic arthritis, ankylosing spondylitis and, in combination with the drug methotrexate, for moderate to severe rheumatoid arthritis.
This year, the drug was approved in Europe and then Japan for slowing or preventing structural damage from rheumatoid arthritis in certain patients, uses similar to what the company is seeking in the U.S.
"We look forward to collaborating with the FDA to fully understand requirements needed to support" approval of the new use, Dr. Jerome A. Boscia of Johnson & Johnson Pharmaceutical Research & Development, said in a statement.
Johnson & Johnson shares revenue with Merck & Co. from Simponi and its predecessor drug, Remicade, which was approved in November 1999. Merck sells them in Europe, Russia and Turkey. J&J markets them in North, Central and South America, the Middle East, Africa and most of the Asia-Pacific region.
J&J reported Simponi revenue of $67 million in the second quarter and $162 million in the first half of the year. Remicade, which is approved for about a dozen uses in treating various immune disorders, brought J&J about $1.4 billion in the second quarter and $2.7 billion in the first six months of 2011.
Because Simponi suppresses part of the immune system, use can result in serious infections, including tuberculosis.
Other possible side effects, some of them rare, include: unusual cancers in children and teenagers, reactivation of the hepatitis B virus, heart failure, liver problems, bruising and bleeding easily, lupus-like symptoms such as shortness of breath and joint, muscle or chest pain, and nervous system problems such as multiple sclerosis.
Sunday, July 24, 2011
IT EXISTS ... .. Cows Milk that Dairy Sensitive People CAN Drink Without Adverse Reaction
Just the thought of drinking milk makes me sick to my stomach because I know what will happen if I do! Trust me it's not pretty and it feels pretty terrible too.
I wanted to post this article from an Australian newspaper about this milk that is actually tolerated by dairy sensitive people.
So....... how do American's go about getting some of this A2 milk??? Knowing there's milk that actually exists that "Does The Body Good" makes me want some!!
THIRD-generation dairy farmer Peter Mulcahy accepted it as a cruel twist of fate that three of his five daughters suffered adverse reactions to milk.
For the youngest, Alexandra, 15, the problem was severe. Just a sip of milk or a lick of ice cream was enough to prompt a rash, major digestive problems and usually vomiting within 10 minutes.
The family's doctor advised that she suffered lactose intolerance and warned her against drinking milk again.
But a chance encounter between Mr Mulcahy and another farmer at a Queensland cattle sale proved the doctor wrong.
It was there that he heard of A2 milk, produced by cows carefully bred to produce milk free of a rogue protein suspected of causing most problems in dairy-intolerant people.
The discovery not only changed Alexandra's life, but also paved the way for Mr Mulcahy and his brothers to become some of the biggest producers of A2 milk in Australia.
A2 milk is one of Australia's fastest-growing grocery lines, with news of its health benefits spreading by word of mouth.
"Alexandra was seven and hadn't been able to drink milk for years," Mr Mulcahy, from Tongala, said. "This bloke told me I should give A2 a try. He said plenty of other people who'd never been able to drink milk were now able to drink as much as they wanted.
"I gave her an eggcup full of A2 and I waited for the usual reaction, but there was none. The next day she had a whole glass. My wife was sceptical, but after a week she was starting to be convinced."
He said any contact with conventional milk - in cheese on a pizza, or ice cream - still made Alexandra sick, but she had never had a problem with A2.
Peter Nathan, chief executive of A2 Milk, said scientists had identified a rogue protein as the problem. The protein, known as BCM7, is believed to have emerged as a mutation in European dairy cows hundreds of years ago.
It is so widespread that now only a third of most dairy herds are free of it.
I wanted to post this article from an Australian newspaper about this milk that is actually tolerated by dairy sensitive people.
So....... how do American's go about getting some of this A2 milk??? Knowing there's milk that actually exists that "Does The Body Good" makes me want some!!
THIRD-generation dairy farmer Peter Mulcahy accepted it as a cruel twist of fate that three of his five daughters suffered adverse reactions to milk.
For the youngest, Alexandra, 15, the problem was severe. Just a sip of milk or a lick of ice cream was enough to prompt a rash, major digestive problems and usually vomiting within 10 minutes.
The family's doctor advised that she suffered lactose intolerance and warned her against drinking milk again.
But a chance encounter between Mr Mulcahy and another farmer at a Queensland cattle sale proved the doctor wrong.
It was there that he heard of A2 milk, produced by cows carefully bred to produce milk free of a rogue protein suspected of causing most problems in dairy-intolerant people.
The discovery not only changed Alexandra's life, but also paved the way for Mr Mulcahy and his brothers to become some of the biggest producers of A2 milk in Australia.
A2 milk is one of Australia's fastest-growing grocery lines, with news of its health benefits spreading by word of mouth.
"Alexandra was seven and hadn't been able to drink milk for years," Mr Mulcahy, from Tongala, said. "This bloke told me I should give A2 a try. He said plenty of other people who'd never been able to drink milk were now able to drink as much as they wanted.
"I gave her an eggcup full of A2 and I waited for the usual reaction, but there was none. The next day she had a whole glass. My wife was sceptical, but after a week she was starting to be convinced."
He said any contact with conventional milk - in cheese on a pizza, or ice cream - still made Alexandra sick, but she had never had a problem with A2.
Peter Nathan, chief executive of A2 Milk, said scientists had identified a rogue protein as the problem. The protein, known as BCM7, is believed to have emerged as a mutation in European dairy cows hundreds of years ago.
It is so widespread that now only a third of most dairy herds are free of it.
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